EZH2, Ki-67 and MCM7 are prognostic markers in prostatectomy treated patients
نویسندگان
چکیده
منابع مشابه
Expression of Ki-67, cyclin D1 and apoptosis markers correlated with survival in prostate cancer patients treated by radical prostatectomy.
OBJECTIVE The study was designed to analyse the prognostic value of proliferation markers Ki-67 and cyclin D1 and apoptosis in prostate cancer (PC) patients treated by radical prostatectomy. PATIENTS AND METHODS Two hundred and eleven patients treated by radical prostatectomy for localised prostate cancer were clinically followed up for a mean of 7.3 years. The primary histopathological speci...
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OBJECTIVE Tumor stem cells have been found in a variety of neoplasms and stated to have a role in tumor progression. This study aimed to evaluate the prognostic significance of biomarkers which are said to be related to these cells, i.e., EZH2, ALDH1 and Ki-67, and their correlation with each other in astrocytic gliomas. MATERIAL AND METHOD Formalin-fixed, paraffin-embedded tissue specimens o...
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Triple-negative breast cancer (TNBC) is an aggressive subgroup of breast cancer lack of effective target therapy. This study was to investigate the prognostic role of p53 and Ki-67 in 156 cases of TNBC patients. Logistic regression analysis was used to examine the association between clinical parameters and recurrence. Univariate and multivariate analyses were used to examine the association be...
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PURPOSE This pilot study aimed to evaluate prognostic factors of postmastectomy radiotherapy (PMRT) for breast cancer patients undergoing systemic therapy in either preoperative or postoperative setting. METHODS Between 2003 and 2009, 113 patients received PMRT: 61 underwent preoperative systemic therapy (PST subgroup) and 52 received postoperative systemic therapy (non-PST subgroup). RESUL...
متن کاملKi-67 as a controversial predictive and prognostic marker in breast cancer patients treated with neoadjuvant chemotherapy
BACKGROUND Studies have partly demonstrated the clinical validity of Ki-67 as a predictive marker in the neoadjuvant setting, but the question of the best cut-off points as well as the importance of this marker as a prognostic factor in partial responder/non-responder groups remains uncertain. METHODS One hundred twenty patients diagnosed with invasive breast cancer and treated with neoadjuva...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2007
ISSN: 0020-7136,1097-0215
DOI: 10.1002/ijc.23145